Synthesis of Biscardanol as Key Intermediary in Preparation of Bistioxanthones

Synthesis of Biscardanol as Key Intermediary in Preparation of Bistioxanthones

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The cashew nut shell liquid (CNSL) is an important source of phenolic compounds such as anacardic diablo 2 amn acids, cardols and cardanols.These compounds present many biological activities.The components of CNSL were isolated and purified by column chromatography.

Cardanol was employed as starting material for aptamil allerpro a methathesis reaction making use of Grubbs 1st generation catalyst, under nitrogen atmosphere, in dichloromethane, heating at 50 oC and, magnetic stirring during 98 h.The product biscardanol is a key-intermediate for the synthesis of new bis thioxanthones.